Laboratory findings concomitantly consistent with a TMA: acute kidney injury, anemia (hemoglobin 9.1 to 8.1 g/dL), thrombocytopenia (platelets 25,000 K/CMM), an elevated LDH (350 unit/L) (normal range 98–192 unit/L) and suppressed haptoglobin (<8 mg/dL) with reticulocyte count of 6.5%, reflecting adequate bone marrow response, all supported a diagnosis of acute hemolytic anemia. The gene discussed is HP; the disease is Thrombocytopenia.