The AUC was 0.782 (0.722 ~ 0.842) for the traditional model, which was constructed by using selective baseline variables including age, sex, diabetes mellitus, hypertension, ischemic heart disease, chronic obstructive pulmonary disease, CKD, stroke, Na, Cr, Hb and EF. The gene discussed is GSTM1; the disease is chronic obstructive pulmonary disease.