Accordingly, no differences in foam cell formation were noted in BMDMs stimulated with oxLDL for 24 hours, as revealed by flow cytometric analyzes of Nile Red staining in BMDM derived from Ldlr-/- compared to Ldlr-/-Batf3-/- mice (Panel D in S3 Fig), suggesting a minor, if any, role of Batf3 in macrophages in atherosclerosis. The gene discussed is BATF3; the disease is atherosclerosis.