Despite differing reports regarding the expression levels of TGF-β1 or patterns of connective tissue composition in CRSwNP, it is generally understood that the expression of IL-25 is significantly higher in the nasal polyps of CRSwNP patients than in CRSsNP patients or control subjects [3]. The gene discussed is TGFB1; the disease is chronic rhinosinusitis with nasal polyps.