After adjusting for age, sex, education, smoking, alcohol drinking, BMI, LDL cholesterol, hypertension, eGFR, and study center, there was no association between a difference in the 75th versus the 25th percentile of urine arsenic and fibrinogen (GMR: 0.99, 95% CI: 0.98, 1.01), PAI-1 (GMR: 1.01, 95% CI: 0.97, 1.06), or CRP (GMR: 0.95, 95% CI: 0.87, 1.02) among SHFS participants without diabetes (S5 Table, Model 2; S3 Fig). This evidence concerns the gene CRP and diabetes mellitus.