Lin et al reported that the serum thrombomodulin level predicted mortality (hazard ratio 1.19) in adults with sepsis [10], and Krafte-Jacobs et al reported 1.5- and 3-fold higher serum thrombomodulin levels in pediatric patents who survived and died from septic shock, respectively, compared to healthy controls [13]. The gene discussed is THBD; the disease is Sepsis.