Recently, Ceyhan-Birsoy et al. screened 708 HCM patients for CNVs using a NGS panel including 18 HCM-related (or putative) genes or 46 genes covering the full spectrum of cardiomyopathies, and detected CNVs in 4 of them (0.56%): a duplication in MYOZ2; a deletion in MYBPC3; a whole gene duplication of NEXN; and a whole gene duplication of GLA, LAMP2, EMD and TAZ (patient with trisomy X) [24]. The gene discussed is MYOZ2; the disease is cardiomyopathy.