SERPINF1 and hepatocellular carcinoma: According to the results of immunohistochemical (IHC) staining for PEDF, 149 HCC patients were divided into 2 groups: a high-PEDF-expression group (score of 3 or 4) and a low-PEDF-expression group (weak or no staining, score of 0, 1 or 2) (Figure 1c).