MTOR and gastric cancer: In vitro analysis revealed that Ginseng extract had strong anti-proliferative and pro-apoptotic effects on KATO3 human gastric cancer cells via the upregulation of Bax (B-cell lymphoma 2-associated X protein), IκBα (nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor α) proteolysis, and the blocking of mTOR (mammalian target of rapamycin) and protein kinase B signaling [80].