One notable recurrent rearrangement is the 16p13 zinc finger CCCH-type containing 7Abreast cancer anti-estrogen resistance 4 (ZC3H7A-BCAR4) fusion, which together with copy number gain of the locus containing BCAR4 (16p13.13, found in 20% of tumors) and duplication detected by whole genome sequencing suggest a potential role of this gene in cervical carcinogenesis [18]. The gene discussed is BCAR4; the disease is cancer.