Both TWIST genes were reported overexpressed in many types of cancers: prostate, breast, cervical, endometrial, ovarian, head and neck cancer, oesophageal squamous cell carcinoma, gastric, hepatocellular carcinoma, pancreas, colon, kidney, glioma, melanoma, neuroblastoma, parathyroid, pheochromocytoma, sarcoma [41,43] and also NSCLC [44]. Here, TWIST1 is linked to cancer.