More recently, in a humanised HLA-transgenic mouse model of islet autoimmunity, Gibson and colleagues demonstrated that, while peptide presented by tolerogenic dendritic cells controlled autoimmunity and was associated with islet-specific IL-10 production, intradermal injection of the same peptide also reduced autoimmunity and increased the proliferation of FOXP3+ Tregs [87]. Here, FOXP3 is linked to Autoimmunity.