Alterations in the Treg population in type 1 diabetes include increased levels of Treg apoptosis [25, 26], a decrease in the stability of FOXP3 expression [33, 34] and an increase in the frequency of Tregs that produce proinflammatory cytokines, such as IFN-γ and IL-17 [35, 36]. Here, IL17A is linked to type 1 diabetes mellitus.