Notably, since CENPF regulates several genes important for metastasis, including MMP2, MMP9, LOX, CXCR4, and CXCL12, dysregulation of the miRNA-COUP-TFII-FoxM1-CENPF axis can inhibit also PCa metastatization [86]. The gene discussed is FOXM1; the disease is posterior cortical atrophy.