Modern pharmacological evidence suggests that the total glycosides of paeoniae extracts from radix paeoniae alba could reduce serum immunoglobulin and erythrocyte sedimentation rate, improve symptoms such as xerophthalmia and xerostomia [24], and have bidirectional regulation effects on the proliferation of T and B lymphocytes to some extent, promoting or inhibiting the production of interleukin 1, interleukin 2, and tumor necrosis factor [25]. Here, TNF is linked to Keratoconjunctivitis sicca.