In another epigenome-wide association study, conducted to reveal prioritized genes and pathways with statistically significant DNA methylation changes in PD, followed by a subsequent replication analysis of top-ranked CpG sites, single CpG sites of FANCC and TNKS2 showed significant differential methylation between PD cases and controls (Moore et al., 2014). The gene discussed is TNKS2; the disease is Parkinson disease.