EPHA4 and major depressive disorder: Using postmortem brain samples from the Neuropathology Consortium of the Stanley Medical Research Institute28, 29, we found that the p-EphA4/EphA4 ratio was significantly higher in the parietal cortex (Brodmann area 7: BA7) of subjects with depression and bipolar disorder, but not schizophrenia, than in that of controls (one-way ANOVA, F1,59 = 5.302, P = 0.003) (Fig. 1g).