ITGAM and infection: As shown in Fig. 9, both LC and iDDC exhibited downregulation of major histocompatibility complex (MHC) class I expression at 24 and 48 h postinfection, while the expression of MHC class II (HLA-DR), CD1a, and CD11b was not altered at 24 h of infection but showed a slight downregulation at 48 h in LC, as indicated by the mean fluorescence intensity (MFI).