TOR1A and early-onset generalized limb-onset dystonia: The best studied EOTD mutation is the deletion of a GAG codon in the DYT1 gene, which eliminates a glutamate residue (ΔE) at position 302/303 in the protein torsinA (torsinAΔE) (Klein et al., 1998; Ozelius et al., 1998, 1997, 1992; Kramer et al., 1994).