These data in fibroblasts from manifest PARK6 patients at advanced age confirmed the previous findings in starving neuroblastoma cells, verifying that the loss of function of PINK1 leads to a deficit of the mitochondria-associated antiviral RNA sensor IFIT3, in parallel to a supersensitive induction of downstream RSAD2 (viperin) as an inhibitor of many RNA and DNA viruses. The gene discussed is RSAD2; the disease is neuroblastoma.