PINK1 and neuroblastoma: In view of the strong PINK1-dependent dysregulation of several sensors of pathogenic RNA and of an RNA-virus budding suppressor, namely RSAD2, IFIT3, and IFIT1 in the starvation experiment (Fig. 3c, h, i), we also stressed both cell types (neuroblastoma and MEF cells) with poly(I:C) as a pathogenic RNA-analogue and determined the transcriptional response after 16 h (Fig. 4a).