THBS1 and posterior cortical atrophy: The measurement of 359 serum samples from PCa positive (n = 167) and negative (n = 192) patients with elevated PSA (2–10 ng/ml) revealed a significantly improved accuracy (P <0.001) when two of the glycoproteins (CTSD and THBS1) were combined with %fPSA and age (AUC = 0.8109; P <0.0001; 95% CI = 0.7673–0.8545).