In this study setting, only THBS1 and %fPSA were significantly different in abundance in univariate analysis between the PCa positive and negative group, but CTSD proofed to have an additional statistically significant (P = 0.001) benefit when combined with THBS1, while ICAM1 and OLFM4 did not. Here, OLFM4 is linked to posterior cortical atrophy.