The dMMR vs pMMR CRC were more likely to be stage IIA (16.6%) vs others (stage I: 9.1%, stage IIB: 8.0%, stage IIC: 19.0%, stage IIIA: 10.9%, stage IIIB: 8.4%, stage IIIC: 11.9%, stage IVA: 5.3%, stage IVB: 4.3%, P <0.001), right colon (22.5%) vs left colon (7.4%) and rectum (6.2%) (P < 0.001), from men (11.6%) vs women (8.7%) (P = 0.031), and poor or undifferentiated (23.6%) vs well or moderate differentiation (9.6%) (P < 0.001), young age (20–39 years old, 13.8%) vs old age (40–59 years, 12.2%; 60–85 years old, 8.3%; P = 0.001), ERCC1 negative (23.1%) vs ERCC1 positive (9.1%) (P< 0.001). The gene discussed is ERCC1; the disease is colorectal carcinoma.