41 rare variants with MAF< 0.05% were present in 20 different genes (ANK2, CACNB2, COX15, DSP, EYA4, FLNC, KCNE1, KCNH2, KCNJ5, KCNQ1, MYBPC3, MYH6, MYLK2, MYOM1, NEXN, PSEN1, RBM20, SCN1B, SOS1, TTN) (see S6 Table—Rare cardiomyopathy variants with AGMG score). This evidence concerns the gene SOS1 and cardiomyopathy.