Copy number data in various human tumors published in TCGA database (access through cBioPortal (http://www.cbioportal.org; accessed 18 Aug 2016) (Gao et al., 2013) show that homozygous TP53 genomic deletion occurs in various human cancers, at frequencies ranging from 1% to 15% (Figure 1A, Figure 1—figure supplement 1A). Here, TP53 is linked to cancer.