13 identified 18 down‐regulated and 19 up‐regulated miRNAs in fibrotic livers, of which miR‐30a was down‐regulated in a NASH model in C57BL/6 mice, and studies have reported that miR‐30a is a key regulator of myocardial fibrosis 14 and peritoneal fibrosis 15. Peng et al. 16 reported that miR‐30a can inhibit the epithelial–mesenchymal transition. Zhu et al. 17 reported that Beclin1, a key autophagy‐related gene, was a possible target for miR‐30a, which negatively regulated Beclin1 to inhibit autophagic activity. This evidence concerns the gene BECN1 and metabolic dysfunction-associated steatohepatitis.