Finasteride and dutasteride treatments resulted in nonsignificantly decreased AR expression in tumors in most groups, which is not consistent with increased AR expression in castrated TRAMP mice small and large tumors [45], tumors from men who received androgen deprivation therapy for prostate cancer [46], and LNCaP human prostate cancer cells treated with finasteride [47]. This evidence concerns the gene AR and Familial prostate cancer.