IFNG and infection: This quantity is higher than the plasma IFN-γ concentrations of ca. 20 pg/ml reported for individuals with severe infection [14], however during immunotherapy serum levels of IFN-γ can rise to over 100 pg/ml for periods of up to 12 h after administration of a dose of 100 μg/m2 [15], which is the dosage used in cases using IFN-γ to treat IA [8].