The most common drug-related AEs were diarrhea (grade 1/2, 78%), fatigue (grade 1/2, 67%), anemia (grade 1/2, 44%), rash (grade 1/2, 32%), elevated AST or ALT (grade 1/2, 32%), and nausea (grade 1/2, 32%) (Fig. 1). Here, GPT is linked to anemia (phenotype).