CDH2 and esophageal squamous cell carcinoma: Recently, a study on the pathology of ESCC patients revealed that several phenotypes such as epithelial-like (E-cadherin: positive/vimentin- or N-cadherin: negative), mesenchymal-like (E-cadherin: negative/vimentin- or N-cadherin: positive), hybrid type (E-cadherin: positive/vimentin- or N-cadherin: positive), and null type (E-cadherin: negative/vimentin- or N-cadherin: negative) exist in ESCC patients [38].