IGHE and infection: Hypotheses to explain these last findings could be related to: i) the serum available from the CC1 was taken just during patient’s hospitalization (i.e. few days after the infected fish intake); on the other hand, it has been reported that IgE reaction against Ani s 1 increased after 1 month from the infection [2, 36, 37]; ii) in both CC1 and CC2 cases, the parasite larva was found, at least, during the first 7 days after the infection.