The frequency of jaundice was lower in neonatal Cxcr2-/- mice 14 days after RRV when their mothers received SMZ/TMP (100% in regular diet vs. 52.4% in SMZ/TMP, P < 0.0001; Fig 1A), along with improved survival when compared to regular diet (0% in regular diet vs. 55.8% in SMZ/TMP, P < 0.0001; Fig 1B). This evidence concerns the gene CXCR2 and Jaundice.