ALDH7A1 and Duchenne muscular dystrophy: [13–15] They also revert back to normal after adeno-associated virus (AVV) vector therapy in Golden Retriever Muscular Dystrophy (GRMD) dogs, a canine model for DMD.[16] However, longitudinal assessments using 31P MRS in DMD are very limited and hence it is unknown how PDE changes over time in the same individual muscle.[14] Since muscles in DMD patients become affected at different time-points and at different rates it is essential to perform muscle specific measurements.[17, 18]