According to the evidence that mutation and rearrangement imputable to ALK are associated with other malignancies, including non-small cell lung cancer (NSCLC) [200], anaplastic large cell lymphoma (ALCL) [201] and other types of neonatal cancer such as rhabdomyosarcoma [202,203,204,205], a recently reported type of congenital lung lesion (fetal lung interstitial tumor) [206] and inflammatory myofibroblastic tumors [207], the inhibition of the aberrant ALK kinase function could be a viable therapeutic option for different pathologies, besides pediatric NB. Here, ALK is linked to non-small cell lung carcinoma.