ALK and non-small cell lung carcinoma: In the study described in this report, we compare a commercially available RT-PCR assay (ALK RGQ RT-PCR Kit, QIAGEN, Manchester, UK) designed to identify mRNA produced by all ALK rearrangements regardless of the fusion partner or variant (Figure 1), with IHC that detects the ALK protein and FISH that directly identifies ALK genomic rearrangements in FFPE samples from patients with NSCLC.