EGFR and neoplasm: The core α-1,6-fucose structure, which is catalyzed by fucosyltransferase-8 (FUT8) in mammals, has been reported to be upregulated in tumor progress [22,23], and participates in the regulation of the EGFR (Epidermal Growth Factor Receptor) signal pathway or in the regulation of the function of immunoglobulin [24].