Transcript levels of RBM3 are elevated in cell lines immediately following cold shock (when taken from 37 to 32°C) and RBM3 is often co‐expressed with another GRP family member, cold‐inducible RNA‐binding protein.66 Levels of RBM3 have subsequently shown to be elevated across multiple cancers, generally in association with a favorable outcome. The gene discussed is RBM3; the disease is cancer.