Mutations in FUS have so far only been observed in ALS, but not FTLD patients with FUS pathology (ALS-FUS and FTLD-FUS, respectively) (Neumann et al. 2009b; Rohrer et al. 2011; Urwin et al. 2010; Snowden et al. 2011). The gene discussed is FUS; the disease is amyotrophic lateral sclerosis.