TAF15 and cancer: TAF15 was initially associated with cancer, specifically extraskeletal myxoid chondrosarcoma and acute leukemia, in which the N-terminal transactivation domain of TAF15 was translocated and fused to the DNA-binding domain of NR4A3 or CIZ/MNP4, respectively (Sjögren et al. 1999; Martini et al. 2002).