S100B and post-concussion syndrome: In severe TBI, S100B levels more than 1.13 ng/ml were correlated with high mortality (100% sensitivity and 41% specificity).37 In this regard, it was concluded that serum S100B demonstrates the severity of injury and improves the prediction of outcome after severe TBI.9      It is expressed that S100B level few hours post mild TBI is a suitable predictor for post-concussion syndrome in later times.