INSR gene is involved in 12 pathways of which, Type II diabetes mellitus, PI3K-Akt signaling pathway, Insulin signaling pathway (FDR < 0.05) are prominent related to Type 2 Diabetes whereas CCND1 is involved in Jak-STAT signalling pathway apart from PI3K-Akt signaling pathway112. This evidence concerns the gene AKT1 and type 2 diabetes mellitus.