After adjustment for age, sex, BMI, fasting plasma glucose, ALT, HDL cholesterol, and CAP (representing liver steatosis), significant liver fibrosis was independently associated with BMDs at the femur neck (β = –0.18, P = 0.039) and total hip (β = –0.21, P = 0.005) in patients with NAFLD. This evidence concerns the gene GPT and fatty liver disease.