In order to address this issue, we first assessed the serum levels of IL-1α, IL-6, TNF-α, IL-10, IL-12p70, IFN-α2, IFN-β, IFN-ω, IFN-γ, IL-23 and CRP of TB patients from TZ and SA by multiplex bead array analyses (Fig 4). This evidence concerns the gene TNF and tuberculosis.