CD4 and Hepatic fibrosis: The association between the CB2-63 RR variant and HAI score 9–18 was analyzed in a multivariate analysis (Table 3) including as covariates the age at enrolment, HIV RNA (≤ 100 vs. > 100 copies/ml), CD4+cells/mL count (≤ 500 vs. > 500 cells/mL), liver fibrosis stage (absent or mild vs. moderate or severe; 0–3 vs. 4–6) and ART regimen (yes vs. no).