SMARCA1 and cancer: ARID1B is a part of the switch/sucrose non-fermenting (SWI/SNF) complex that is implicated in several cancers.35 More recently a study reported that loss of function in the SWI/SNF complex leads to genomic instability in lung cancer.36 Lung cancer sub-types showed no significant differences between histology, implying that the loss of SWI/SNF function caused genomic instability regardless of lung cancer sub-type, consistent with our observation that ARID1B is a marker for both LUAD and LUSC (Table 1).