Interestingly, when these 13 genes were inspected for possible association with cancer using the COSMIC Cancer Gene Census,21 only REL and ARID1B were found to be previously implicated in cancer.22, 23, 24 When all 13 genes were examined for possible drug-ability, using DrugDB,25REL and ARID1B were found to be clinically actionable. This evidence concerns the gene REL and cancer.