In this regard, MALT1 can be inhibited with several medicinally active phenothiazine derivatives including mepazine and thioridazine, the latter of which is previously used as a dopamine antagonist for psychiatric conditions and recently as an antimicrobial agent for tuberculosis.70, 71 These agents and the newly characterized MALT1 inhibitor MI-2 have shown efficacy in preventing lymphoma progression in preclinical animal studies.40, 41, 42. This evidence concerns the gene MALT1 and tuberculosis.