This warrants investigation as ASCT2 detection by immunohistochemistry has prognostic significance in several cancer types.23, 25, 26 Hassanein et al.41 have performed preclinical studies using 4-[18F]-Fluoroglutamine PET as a non-invasive measure of ASCT2 expression in lung cancer. This evidence concerns the gene SLC1A5 and lung carcinoma.