Above all, these findings revealed erinacine A as one of the definite elements responsible for the NGF-synthesis stimulating and neuroprotective activities of H. Erinaceus, which can be further proved by the fact that erinacine A was able to obviously ameliorate pathologies in Alzheimer’s disease (AD) and Parkinson’s disease (PD) mouse models [25,26]. Here, NGF is linked to Alzheimer disease.