INS and type 2 diabetes mellitus: However, during iv lipid infusions, plasma NEFA concentrations are typically elevated to around 1500 μmol/L or higher [17], which is in excess of the fasting concentrations reported for obese, insulin-resistant individuals (~400 μmol/L) [21], and individuals with poorly managed type 2 diabetes mellitus (T2DM) (~800 μmol/L) [22].