In the DU145 prostate cancer cell line, co-treatment with paclitaxel and TRAIL induced apoptosis in 27.5% ± 3.8% cells in a concentration of 0.25 μM and 28.0% ± 3.4% in a concentration of 0.5 μM after a 48 h incubation, whereas cabazitaxel and TRAIL induced apoptosis in 24.5% ± 3.75% cells in a concentration of 0.25 μM and 24.9% ± 3.9% in a concentration of 0.5 μM in DU145 cells. This evidence concerns the gene TNFSF10 and Familial prostate cancer.