In the study of Ji et al. [61], the overexpression of miRNA-486-attenuated pulmonary fibrosis in mice and repressed TGF-β1-induced fibrogenesis in NIH/3T3 cells, thus demonstrating that miR-486 has a strong antifibrotic activity in lung tissues and may be a novel target in the treatment of pulmonary diseases. This evidence concerns the gene TGFB1 and lung disorder.