Then, we assessed whether the changes in circulating Th1, Th2, and Th17 levels were associated with age, years of hypertension, heart rate, body mass index (BMI), biochemical markers including lipid and lipoprotein fractions, fasting glucose, HbA1C, creatinine, CRP, Hcy, and angiotensin II in hypertensive patients. The gene discussed is CRP; the disease is hypertensive disorder.