Similarly, the proportion of admissions for heart failure was lower in the SGLT2 cohort compared with the DPP4 cohort among matched cohorts of patients with diabetes complication (4.5% SGLT2 vs 6.9% DPP4; aHR 0.68; 95% CI 0.52–0.90; p = .006; Additional file 3: Table S2). This evidence concerns the gene SLC5A2 and heart failure.